pentobarbital will lower the level or effect of parecoxib by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Observe.

pentobarbital will lessen the level or effect of vinorelbine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.

Watch Closely (2)pentobarbital will lessen the extent or effect of oliceridine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. If coadministration with a CYP3A4 inducer is important, consider growing oliceridine dose until stable drug effects are realized; monitor for signs of opioid withdrawal.

pentobarbital will minimize the level or effect of prednisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will reduce the level or effect of avanafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. For patients with ED, monitor reaction diligently due to likely for reduced effectiveness.

pentobarbital will minimize the extent or effect of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not advisable; strong cytochrome P450 enzyme inducers lower systemic publicity to roflumilast and may decrease the therapeutic effectiveness

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pentobarbital will reduce the level or effect of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

pentobarbital will lower the extent or effect of nilotinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will minimize the level or effect of apremilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration with sturdy CYP inducers results in a major reduce of systemic publicity of apremilast, which may bring about lack of efficacy

pentobarbital will reduce the level or effect of doxorubicin liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital read more will lower the extent or effect of rabeprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.

pentobarbital will lessen the level or effect of atazanavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.

Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (name Beforehand used: bishydroxycoumarin) and causes a lower in anticoagulant activity as calculated from the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing improved metabolism and decreased anticoagulant response of oral anticoagulants (e.